The hormonal Zeitgeber melatonin: role as a circadian modulator in memory processing

The neuroendocrine substance melatonin is a hormone synthesized rhythmically by the pineal gland under the influence of the circadian system and alternating light/dark cycles. Melatonin has been shown to have broad appli
The neuroendocrine substance melatonin is a hormone synthesized rhythmically by the pineal gland under the influence of the circadian system and alternating light/dark cycles. Melatonin has been shown to have broad applications, and consequently becoming a molecule of great controversy. Undoubtedly, however, melatonin plays an important role as a time cue for the endogenous circadian system. This review focuses on melatonin as a regulator in the circadian modulation of memory processing. Memory processes (acquisition, consolidation, and retrieval) are modulated by the circadian system. However, the mechanism by which the biological clock is rhythmically influencing cognitive processes remains unknown. We also discuss, how the circadian system by generating cycling melatonin levels can implant information about daytime into memory processing, depicted as day and nighttime differences in acquisition, memory consolidation and/or retrieval.
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Metadaten
Author:Oliver Rawashdeh, Erik Maronde
URN:urn:nbn:de:hebis:30:3-243479
DOI:http://dx.doi.org/10.3389/fnmol.2012.00027
ISSN:1662-5099
Pubmed Id:http://www.ncbi.nlm.nih.gov/pubmed?term=22408602
Parent Title (English):Frontiers in molecular neuroscience
Publisher:Frontiers Research Foundation
Place of publication:Lausanne
Document Type:Article
Language:English
Date of Publication (online):2012/05/25
Date of first Publication:2012/03/06
Publishing Institution:Univ.-Bibliothek Frankfurt am Main
Release Date:2012/05/25
Tag:circadian rhythms; hormone; learning; melatonin; memory; pineal; zebrafish
Volume:5
Issue:Article 27
Pagenumber:6
HeBIS PPN:30395177X
Institutes:Medizin
Dewey Decimal Classification:610 Medizin und Gesundheit
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung 3.0

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