(4R)-4-(Biphenyl-4-yl)-7-chloro-1,2,3,4-tetrahydroquinoline
The title compound, C(21)H(18)ClN, was synthesized by an enanti-oselective Brønsted acid-catalysed transfer hydrogenation reaction. The six-membered heterocycle adopts a half-chair conformation. It has the biphenyl residue in an axial position. The two rings of the biphenyl residue are almost coplanar [dihedral angle = 2.65 (9)°]. The crystal packing is stabilized by N-H⋯Cl hydrogen bonds, which connect the mol-ecules into chains running along the a axis.
| Author: | Thomas Theissmann, Michael Bolte |
|---|---|
| URN: | urn:nbn:de:hebis:30:3-252997 |
| DOI: | http://dx.doi.org/10.1107/S160053681103830X |
| ISSN: | 1600-5368 |
| Pubmed Id: | http://www.ncbi.nlm.nih.gov/pubmed?term=22064825 |
| Parent Title (English): | Acta crystallographica / Section E, Structure reports online |
| Publisher: | Munksgaard |
| Place of publication: | Copenhagen |
| Document Type: | Article |
| Language: | English |
| Date of Publication (online): | 30.09.2011 |
| Date of first Publication: | 30.09.2011 |
| Publishing Institution: | Univ.-Bibliothek Frankfurt am Main |
| Volume: | 67 |
| Issue: | o2747 |
| Institutes: | Biochemie und Chemie |
| Dewey Decimal Classification: | 540 Chemie und zugeordnete Wissenschaften |
| Sammlungen: | Universitätspublikationen |
| Licence (German): |  Creative Commons - Namensnennung 3.0 |
