The statistical production of antibaryons is considered within the canonical ensemble formulation. We demonstrate that the antibaryon suppression in small systems due to the exact baryon number conservation is rather different in the baryon-free (B=0) and baryon-rich (B>1) systems. At constant values of temperature and baryon density in the baryon-rich systems the density of the produced antibaryons is only weakly dependent on the size of the system. For realistic hadronization conditions this dependence appears to be close to B/(B+1) which is in agreement with the preliminary data of the NA49 Collaboration for the antiproton/pion ratio in nucleus-nucleus collisions at the CERN SPS energies. However, a consistent picture of antibaryon production within the statistical hadronization model has not yet been achieved. This is because the condition of constant hadronization temperature in the baryon-free systems leads to a contradiction with the data on the antiproton/pion ratio in e+e- interactions.