Latest documents http://publikationen.stub.uni-frankfurt.de/index/index/ Fri, 24 May 2013 15:28:43 +0200 Fri, 24 May 2013 15:28:43 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30047 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30047 Fri, 24 May 2013 15:28:43 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30046 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30046 Fri, 24 May 2013 15:28:37 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30045 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30045 Fri, 24 May 2013 15:28:33 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30044 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30044 Fri, 24 May 2013 15:26:54 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30043 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30043 Fri, 24 May 2013 15:26:50 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30042 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30042 Fri, 24 May 2013 15:26:47 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30041 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30041 Fri, 24 May 2013 15:26:43 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30040 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30040 Fri, 24 May 2013 15:26:40 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30039 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30039 Fri, 24 May 2013 15:26:11 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30038 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30038 Fri, 24 May 2013 15:26:06 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30037 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30037 Fri, 24 May 2013 15:26:02 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30036 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30036 Fri, 24 May 2013 15:25:58 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30035 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30035 Fri, 24 May 2013 15:25:55 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30034 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30034 Fri, 24 May 2013 15:25:33 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30033 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30033 Fri, 24 May 2013 15:25:30 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30032 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30032 Fri, 24 May 2013 15:25:23 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30031 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30031 Fri, 24 May 2013 15:25:15 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30030 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30030 Fri, 24 May 2013 15:25:11 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30029 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30029 Fri, 24 May 2013 15:19:08 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30028 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30028 Fri, 24 May 2013 14:54:29 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30027 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30027 Fri, 24 May 2013 11:16:13 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30024 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30024 Fri, 24 May 2013 11:00:11 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30023 periodicalpart http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30023 Fri, 24 May 2013 10:48:53 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30005 The current study tested the assumption that floristic and functional diversity patterns are negatively related to soil nitrogen content. We analyzed 20 plots with soil N-contents ranging from 0.63% to 1.06% in a deciduous forest near Munich (Germany). To describe species adaptation strategies to different nitrogen availabilities, we used a plant functional type (PFT) approach. Each identified PFT represents one realized adaptation strategy to the current environment. These were correlated, next to plant species richness and evenness, to soil nitrogen contents. We found that N-efficient species were typical for low soil nitrogen contents, while N-requiring species occur at high N-contents. In contrast to our initial hypotheses, floristic and functional diversity measures (number of PFTs) were positively related to nitrogen content in the soil. Every functional group has its own adaptation to the prevailing environmental conditions; in consequence, these functional groups can co-exist but do not out-compete one another. The increased number of functional groups at high N-contents leads to increased species richness. Hence, for explaining diversity patterns we need to consider species groups representing different adaptations to the current environmental conditions. Such co-existing ecological strategies may even overcome the importance of competition in their effect on biodiversity. Markus Bernhardt-Römermann; Christine Römermann; Valério de Patta Pillar; Thomas Kudernatsch; Anton Fischer article http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30005 Fri, 24 May 2013 09:59:40 +0200 http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30022 Autophagy is a highly regulated program of self-degradation of the cytosolic constituents that has key roles during early development and in adult cell growth and homeostasis. To investigate the role of autophagy in otic neurogenesis, we studied the expression of autophagy genes in early stages of chicken (Gallus gallus) inner ear development and the consequences of inhibiting the autophagic pathway in organotypic cultures of explanted chicken otic vesicles (OVs). Here we show the expression of autophagy-related genes (Atg) Beclin-1 (Atg6), Atg5 and LC3B (Atg8) in the otocyst and the presence of autophagic vesicles by using transmission electron microscopy in the otic neurogenic zone. The inhibition of the transcription of LC3B by using antisense morpholinos and of class III phosphatidylinositol 3-kinase with 3-methyladenine causes an aberrant morphology of the OV with accumulation of apoptotic cells. Moreover, inhibition of autophagy provokes the misregulation of the cell cycle in the otic epithelium, impaired neurogenesis and poor axonal outgrowth. Finally, our results indicate that autophagy provides the energy required for the clearing of neuroepithelial dying cells and suggest that it is required for the migration of otic neuronal precursors. Taken together, our results show for the first time that autophagy is an active and essential process during early inner ear development. Maria Rodriguez Aburto; Hortensia Sánchez-Calderón; Juan M. Hurlé; Isabel Varela-Nieto; Marta Magariños article http://publikationen.stub.uni-frankfurt.de/frontdoor/index/index/docId/30022 Thu, 23 May 2013 17:07:25 +0200